Defining a Physiological Role for the Tubulin Tyrosination Cycle
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Haitham T. Idriss 1 *
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1 Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, PA, USA
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Abstract

This paper proposes, based on data from other laboratories, that the physiological function of the tubulin tyrosination cycle is to maintain a check for normal physiological milieu within cells, whereby tyrosine and nitrotyrosine act as markers for normality and abnormality, respectively. Incorporation of nitrotyrosine is postulated to initiate apoptosis to facilitate elimination of abnormal cells.

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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Article Type: Review Article

https://doi.org/10.29333/ejgm/82183

Eur J Gen Med, 2004 - Volume 1 Issue 2, pp. 1-2

Publication date: 15 Apr 2004

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