An Updated Overview of Herpes Simplex Virus-1 Infection: Insights from Origin to Mitigation Measures
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Abu Tayab Moin 1, Mohammad Al-baruni Chowdhury 1, Sumaiya Hafiz Riana 1, Md. Asad Ullah 2 , Yusha Araf 3, Bishajit Sarkar 2, Abdullah Mohammad Shohael 2 *
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1 Department of Genetic Engineering and Biotechnology, Faculty of Biological Sciences, University of Chittagong, Chattogram, BANGLADESH2 Department of Biotechnology and Genetic Engineering, Faculty of Biological Sciences, Jahangirnagar University, Dhaka, BANGLADESH3 Department of Genetic Engineering and Biotechnology, Faculty of Life Sciences, Shahjalal University of Science and Technology, Sylhet, BANGLADESH* Corresponding Author
Abstract
Purpose: High prevalence of recurrent HSV-1 (Herpes Simplex Virus 1) and its facile mode of transmission requires an elaborated understanding of the virus for mollification. To mitigate its pervasive nature that greatly affects both men and women, a thorough understanding of the viral genome and epidemiology are prerequisites. The review focuses on the existing facts of HSV-1 and acknowledges the prospect of ongoing epidemiological studies.
Findings: Recent data indicates a surge of HSV-1 infection in the age ranged 30-50 years along with the emergence of neonatal cases. The newfound receptors indicate the effect and degree of susceptibility of the host and support the statistical data of HSV-1 seropositivity. Recent studies also show that the evolving virus has gained resistance against widely used antiviral drugs such as Acyclovir (ACV). Therefore, trials of several vaccines (eg. GEN-003and HerpV) are garnering attention as a possible prevention method.
Summary: As most natural viruses are radically evolving, ensuing rather fatal consequences than previous wild types, every virus requires to be tackled with equal importance. Developing vaccines and potent drugs to eradicate viruses from infected subjects’ systems can be the only way to prevent future viral epidemics or pandemics. Therefore, early detection of the virus with accurate assay following immediate treatment can only prevent the cases from future catastrophe.
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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Article Type: Review Article
ELECTRON J GEN MED, 2021, Volume 18, Issue 4, Article No: em299
https://doi.org/10.29333/ejgm/10869
Publication date: 01 May 2021
Article Views: 2770
Article Downloads: 5588
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How to cite this article
Vancouver
Moin AT, Chowdhury MAB, Riana SH, Ullah MA, Araf Y, Sarkar B, et al. An Updated Overview of Herpes Simplex Virus-1 Infection: Insights from Origin to Mitigation Measures. ELECTRON J GEN MED. 2021;18(4):em299. https://doi.org/10.29333/ejgm/10869
APA
Moin, A. T., Chowdhury, M. A.-B., Riana, S. H., Ullah, M. A., Araf, Y., Sarkar, B., & Shohael, A. M. (2021). An Updated Overview of Herpes Simplex Virus-1 Infection: Insights from Origin to Mitigation Measures. Electronic Journal of General Medicine, 18(4), em299. https://doi.org/10.29333/ejgm/10869
AMA
Moin AT, Chowdhury MAB, Riana SH, et al. An Updated Overview of Herpes Simplex Virus-1 Infection: Insights from Origin to Mitigation Measures. ELECTRON J GEN MED. 2021;18(4), em299. https://doi.org/10.29333/ejgm/10869
Chicago
Moin, Abu Tayab, Mohammad Al-baruni Chowdhury, Sumaiya Hafiz Riana, Md. Asad Ullah, Yusha Araf, Bishajit Sarkar, and Abdullah Mohammad Shohael. "An Updated Overview of Herpes Simplex Virus-1 Infection: Insights from Origin to Mitigation Measures". Electronic Journal of General Medicine 2021 18 no. 4 (2021): em299. https://doi.org/10.29333/ejgm/10869
Harvard
Moin, A. T., Chowdhury, M. A.-B., Riana, S. H., Ullah, M. A., Araf, Y., Sarkar, B., and Shohael, A. M. (2021). An Updated Overview of Herpes Simplex Virus-1 Infection: Insights from Origin to Mitigation Measures. Electronic Journal of General Medicine, 18(4), em299. https://doi.org/10.29333/ejgm/10869
MLA
Moin, Abu Tayab et al. "An Updated Overview of Herpes Simplex Virus-1 Infection: Insights from Origin to Mitigation Measures". Electronic Journal of General Medicine, vol. 18, no. 4, 2021, em299. https://doi.org/10.29333/ejgm/10869