Two Cases of Hiccups due to Gastroesophageal Reflux Disease
Cem Koçkar 1, Mehmet İşler 1, Erkan Cüre 1 * , Altuğ Şenol 1, Abdulkadir Baştürk 1
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1 Süleyman Demirel University, School of Medicine, Department of Gastroenterology, Isparta, Turkey
* Corresponding Author


Hiccup is a spasmodic, involuntary contraction of the inspiratory muscles, associated with delayed, abrupt glottic closure, causing a peculiar sound. There are numerous causes of hiccup, including diseases of the gastrointestinal tract. Hiccup is reported to represent an atypical manifestation of the gastroesophageal reflux disease (GERD). We report two cases with hiccup due to GERD. Endoscopic examinations showed esophagitis, Los Angeles class grade A and B, in two cases whose hiccups were improved by proton pump inhibitors (PPI). Hiccup is atypical symptom of GERD. If hiccup is due to GERD, then it may be improved with ppi therapy.


This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Article Type: Case Report

EUR J GEN MED, 2009 - Volume 6 Issue 4, pp. 262-264

Publication date: 15 Oct 2009

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Article Downloads: 606

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