Stem Cells and Myocardial Regeneration
E. Michael Molnar 1 *
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1 Bio-Cellular Research Organization, Barksdale Professional Center, Newark, DE, USA* Corresponding Author

Abstract

Cardiomyocytes lose their ability to proliferate after birth and so heart muscle fibers cannot regenerate. For that reason myocardial injury, such as myocardial infarction (MI), heals by replacement of contractile heart muscle fibers by fibrotic tissue scar, which not only cannot participate in pumping of blood, it does not even contribute to passive mechanics of heart. Massive loss of cardiomyocytes after MI is a common cause of heart failure (HF), which is a consequence of many other cardiovascular diseases, and serious public health problem.

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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Article Type: Review Article

EUR J GEN MED, 2004, Volume 1, Issue 4, 7-14

https://doi.org/10.29333/ejgm/82238

Publication date: 15 Oct 2004

Article Views: 1038

Article Downloads: 621

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