Primary breast lymphoma treated with r-chop chemotherapy
Bülent Karagöz 1 * , Oğuz Bilgi 1, Alev Akyol Erikçi 2, Alpaslan Özgün 1, Orhan Türken 1, Emin Gökhan Kandemir 1
More Detail
1 GATA Haydarpasa Training Hospital Department of Medical Oncology, İstanbul, Turkey
2 GATA Haydarpasa Training Hospital Department of Hematology, İstanbul, Turkey
* Corresponding Author


Primary breast lymphoma is rare disease which is treated with surgery, radiotherapy and chemoterapy. There is little experience of rituximab treatment is in breast lymphoma. Here we present a case of primary breast lymhoma treated with rituximab and chemotherapy combination. A 58-year-old woman referred for left breast mass. Radiologic imaging showed a mass of 4 cm in diameter. Pathologic examination of excisional biopsy specimen revealed Diffuse Large B Cell Lymphoma with CD20 positivity. The patient was stage IE (Ann Arbor). Mastectomy, lumpectomy or axillary dissection were not performed. Six courses of R-CHOP (CHOP plus rituximab) chemotherapy and radiotherapy were given. The complete response was obtained. The patient has been followed for 36 months with no evidence of disease recurrence. This is one of the first cases treated with rituximab. She has been followed for more than 36 months without relapse.


This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Article Type: Case Report

EUR J GEN MED, 2009 - Volume 6 Issue 3, pp. 187-188

Publication date: 15 Jul 2009

Article Views: 878

Article Downloads: 451

Open Access References How to cite this article