Obesity indices as risk factor for colorectal cancer in patients at a national police hospital in Peru
Diego A Flores-Napa 1 , Lucy E Correa-López 1 * , Jenny Raquel Torres-Malca 1 , Willer D Chanduví Puicón 1 , Víctor Juan Vera-Ponce 1 , Jhony A De La Cruz-Vargas 1
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1 Instituto de Investigaciones en Ciencias Biomédicas, Universidad Ricardo Palma, Lima, PERU* Corresponding Author

Abstract

Introduction: Colorectal cancer (CRC) represents the third most diagnosed form of cancer around the world, accounting for 11% of all cancer diagnoses. It has been seen that obesity is closely linked to this disease.
Materials and methods: This study is a non-paired case-control study. To measure obesity, the body mass index (BMI), new body mass index (NBMI), and the triponderal index (TPI) were used. Logistic regression was used to obtain the adjusted odds ratio (aOR) by age and sex, confidence interval (95%CI).
Results: The sample was 246 patients. The prevalence of obesity according to BMI was 12.20%. The multivariable analysis found statistically significant association between CRC and obesity according to BMI (aOR: 3.23; 95% CI 1.26-8.30) compared to normal weight; NBMI tertile 3 (aOR: 4.02; 95% CI 1.95-8.30), compared to tertile 1; and TPI tertile 3 (aOR: 4.55; 95% CI 2.21-9.35) versus tertile 1.
Conclusions: Obesity, is a risk factor for CRC. Future studies might consider useful different ways to measure obesity to define population strata with a higher-risk of CRC.

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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Article Type: Original Article

ELECTRON J GEN MED, 2023, Volume 20, Issue 4, Article No: em492

https://doi.org/10.29333/ejgm/13149

Publication date: 01 Jul 2023

Online publication date: 03 Apr 2023

Article Views: 682

Article Downloads: 611

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