Deniz Tuncel 1 * , Hasan Uçmak 2, Mustafa Gokce 1, Uygar Utku 1
More Detail
1 Kahramanmaras Sutcu Imam University Medical Faculty, Department of Neurology, Kahramanmaraş, Turkey
2 Kahramanmaras Sutcu Imam University Medical Faculty, Department of Clinical Microbiology and Infectious Diseases, Kahramanmaraş, Turkey
* Corresponding Author


In 5-10% of cases of brucellosis may lead to central nervous system manifestation presenting most often as a meningitis or meningoencephalitis. We report three neurobrucellosis who have different presentation. First patient; a 49-year-old-woman who developed diffuse cerebral white matter lesions as leukoencephalopathy associated with neurobrucellosis, presented with gait disturbance, behavior change and seizure. Second patient; 44-year-old man was admitted to our hospital with a complaint of progressive motor weakness in his bilateral legs for four months and headache for one year. The patient’s symptoms may be explained with myeloradiculopathy and meningoencephalitis but the clinical picture didn’t correlate with imaging findings. Third patient; 23-year-old man was admitted to our hospital with a complaint of transient numbness attacks in his left of face and hand and headache for twenty days. He presented as meningitis which is the most clinical presentation of neurobrucellosis and meningovascular complications. Conclusively, brucellosis is still endemic in Turkey and thus neurobrucellosis should be considered in the unexplained neurological symptoms such as cognitive dysfunction, young transient ischemic attacks, paraparesis and psychiatric symptoms.


This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Article Type: Original Article

EUR J GEN MED, 2008 - Volume 5 Issue 4, pp. 245-248

Publication date: 15 Oct 2008

Article Views: 870

Article Downloads: 921

Open Access References How to cite this article