Metformin: A stroke of luck
Mohamad Aljofan 1 * , Abduzhappar Gaipov 2
More Detail
1 Department of Biomedical Sciences, Nazarbayev University School of Medicine. Nur-Sultan city, Kazakhstan
2 Department of Clinical Sciences, Nazarbayev University School of Medicine. Nur-Sultan city, Kazakhstan
* Corresponding Author


Metformin is an oral glucose-lowering drug that has been widely used for more than half a century. Both the American Diabetes Association and the European Association for the study of Diabetes recommend metformin as the first line therapy for the treatment of type II diabetes mellitus. Metformin has considerably evolved from being an antidiabetic into a drug with a wider potential of therapeutic uses such as anticancer, antiaging, treatment of gestational hypertension, preeclampsia and weight loss. In addition to the in-label use of metformin as an anti-hyperglycemic medication, it is widely prescribed as an off label therapy for young women with Poly Cystic Ovary Syndrome for the treatment of symptoms associated with the disorder. This article is a brief summary that lists and briefly discusses current and potential non-hyperglycemic uses and effects of metformin.


This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Article Type: Review Article

ELECTRON J GEN MED, 2019 - Volume 16 Issue 3, Article No: em143

Publication date: 16 May 2019

Article Views: 1416

Article Downloads: 1077

Open Access Disclosures References How to cite this article