Locally advanced cancer of the tongue base: A new method of surgical treatment
I. A. Zaderenko 1 2, A. M. Mudunov 1 2, S. Y. Ivanov 2 3, S. B. Alieva 1, A. V. Nazarenko 1, A. A. Muraev 2, A. M. Avanesov 2, V. T. Tsiklauri 1, A. E. Kazimov 1
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1 Federal State Budgetary Institution «N.N. Blokhin National Medical and Research Center of Oncology» of the Ministry of Healthcare of the Russian Federation, Moscow, 115478, Kashirskoe shosse 23, Russia
2 RUDN University, Department of Maxillo-facial Surgery and Operative Dentistry, Moscow, 117198, Miklukho-Maklaya Street 10, Russia
3 I.M. Sechenov First Moscow State Medical University, 8/2 Trubetskaya St., 119991, Moscow, Russia


Patients are characterized by locally advanced tumours in 70-80% of cases at presentation. Thus, the possibilities for curing and surgical treatment are limited. Total glossectomy, which involves tongue base resection, is associated with severe and permanent disabilities. Total glossectomy leads to severe dysphagia, alalia and social maladjustment. A number of issues motivated us to develop a new method of surgical treatment of locally advanced base of tongue cancer.

To introduce new opportunities for surgical treatment of locally advanced cancer of the tongue base.

Materials and Methods:
Glossectomy was accomplished in five patients suffering from tongue cancer and admitted to N.N. Blokhin National Medical and Research Center of Oncology. Swallowing and speech were preserved in all 5 cases.

We developed a new technique of surgical treatment of locally advanced cancer of the tongue base.

The developed surgical technique allows early rehabilitation. Patients are able to breath effortlessly, swallow and speak. Permanent tracheostomy and PEG tubes are not necessary. All patients remained socially active.


This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Article Type: Original Article


ELECTRON J GEN MED, 2019 - Volume 16 Issue 1, Article No: em104

Publication date: 28 Dec 2018

Article Views: 1197

Article Downloads: 1214

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