Is liquid-based cervical cytology test more effective than conventional pap smear?
İlknur Alkan-Kuşabbi 1, Hüseyin Aydoğmuş 1, Hatice Işık 2, Ali Seven 3, Beril Yüksel 3, Gülenay Gençosmanoğlu-Türkmen 1 4, Deniz Karçaaltıncaba 1 5, Yusuf Ergün 1, Muzaffer Çaydere 6, Sertaç Batıoğlu 1
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1 Ankara Education and Research Hospital, Department of Obstetrics and Gynecology, Ankara, Turkey
2 Ankara, Turkey
3 Kütahya Dumlupınar University, Department of Obstetrics and Gynecology, Kütahya, Turkey
4 Zekai Tahir Burak Education and Research Hospital, Department of Obstetrics and Gynecology, Ankara, Turkey
5 Gazi University Faculty of Medicine, Department of Obstetrics and Gynecology, Ankara, Turkey
6 Ankara Education and Research Hospital, Department of Pathology, Turkey

Abstract

Introduction:
To evaluate and compare the efficiencies of cytologic test methods conventional Pap smear (CVS) versus Thin Prep liquid-based cytology technique (TPT) in the histologic diagnosis of the precancerous lesions of the cervix and cervical cancer.

Material and Methods:
We selected randomly 1203 non-gravid women who were admitted to gynecology and menopause out-patient clinics of our hospital in the study. The cervical smear tests of all women were evaluated both using the conventional Pap smear and the TPT. Cytological examinations were compared according to their adequacy for evaluation. The evaluation of samples were performed and compared according to The Bethesda System.

Results:
The two screening methods were statistically compatible for evaluating the samples (κ=0,379 and p<0,001). The diagnosis interpreted by CPS and TPT methods were synchronous and this was also statistically significant (ĸ=0,829 ve p<0,001).

Conclusions:
Our cytohistologic diagnoses and samples' adequacy interpreted with CVS and TPT were statistically significantly synchronous.

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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Article Type: Original Article

https://doi.org/10.29333/ejgm/81871

Eur J Gen Med, 2017 - Volume 14 Issue 1, pp. 5-8

Publication date: 05 Jan 2017

Article Views: 288

Article Downloads: 78

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