Factors Affecting Survival in Small Cell Lung Cancer
Abdullah Sakin 1 * , Erhan Sadık Turgut 2, Muruvvet Aybek 3, Ahmet A. Usta 3, Özgür Koşan 4, Kenan Çelik 5, Savaş Öztürk 5, Murat Koçer 3
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1 Okmeydanı Training and Research Hospital, Medical Oncology Clinic, Istanbul
2 Kanuni Sultan Süleyman Training and Research Hospital, Chest Diseases Clinic, Istanbul
3 Süleyman Demirel University, Medical Oncology Clinic, Isparta
4 Süleyman Demirel University, Department of Biometrics and Genetics, Isparta
5 Haseki Training and Research Hospital, Clinic of Internal Medicine, Istanbul
* Corresponding Author

Abstract

Background:
Small cell lung cancer (SCLC) constitutes about 15-25 % of lung cancers with high mortality rate. Herein we observed the effect of parameters at the time of diagnosis to survival of cases with SCLC.

Methods:
We evaluated 65 patients who were followed up in our oncology department retrospectively.

Results:
Tumor location and stage at the time of diagnosis, smoking history, accompanying comorbidities, ECOG PS, laboratory parameters and treatments applied in pursuit were evaluated. 3-month survival rate of patients was 75.9%, 50.2% for 6-month, 21.4% for 1 year, and 5.5% for 2 years during follow up. ECOG PS and stage were found statistically significant risk factors in model created to determine overall survival.

Conclusion:
Performance score at the time of diagnosis, stage and presence of liver metastasis are identified as prognostic factors for SCLC and of these factors are quite valuable to predict the clinical outcome.

License

This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Article Type: Original Article

https://doi.org/10.29333/ejgm/81903

Eur J Gen Med, 2016 - Volume 13 Issue 3, pp. 37-41

Publication date: 06 Aug 2016

Article Views: 568

Article Downloads: 343

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