Exosomes in cancer therapy: Advances and current challenges
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Rajib Dhar 1 , Arikketh Devi 1 , Shankargouda Patil 2 , Marcos Roberto Tovani-Palone 3 4 *
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1 Cancer and Stem Cell Biology Laboratory, Department of Genetic Engineering, SRM Institute of Science and Technology, Kattankulathur, Tamil Nadu 603203, INDIA2 College of Dental Medicine, Roseman University of Health Sciences, South Jordan, Utah 84095, USA3 Department of Research Analytics, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences (SIMATS), Chennai, Tamil Nadu 600077, INDIA4 Department of Pharmacy and Pharmacology, SRM College of Pharmacy, SRM Institute of Science and Technology, Kattankulathur, Tamil Nadu 603203, INDIA* Corresponding Author

Abstract

Exosomes are subpopulations of extracellular vesicles (EVs) secreted by cells in normal or pathological conditions. From an oncological point of view, such vesicles are involved in cancer progression and may function as a therapeutic tool (based on EVs source), whose molecular signature plays a significant role in the investigation of cancer biomarkers. Recent research reveals the potential role of exosomes in anticancer drug delivery. In this article, we briefly discuss current theranostics perspectives on exosomes and their future orientation.

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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Article Type: Perspective Article

ELECTRON J GEN MED, 2023, Volume 20, Issue 5, Article No: em524

https://doi.org/10.29333/ejgm/13456

Publication date: 01 Sep 2023

Online publication date: 04 Jul 2023

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Article Downloads: 646

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