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Abstract
Purpose: We aimed to investigate the antibiotic resistance characteristics of bacterial pathogens causing lobar pneumonia (LP) in children and the treatment outcomes of these individuals.
Methods: 123 children diagnosed with LP in 2020 were enrolled in this study. Nasopharyngeal swab culture and antibiogram were performed on all patients.
Results: The group aged 24-60 months old was the most common. The most common bacterial pathogens were S. pneumoniae (37.5%), H. influenzae (34.5%) and M. catarrhalis (18.7%). S. pneumoniae showed high resistance to trimethoprim-sulfamethoxazole, clindamycin and cefuroxime. H. influenzae was resistant to cefuroxime and ampicillin (> 80%). M. catarrhalis was resistant to cefuroxime, trimethoprim/sulfamethoxazole and macrolide (> 50%). The third-generation cephalosporin/aminoglycoside combination was the most commonly used as the initial treatment (69.1%), with relatively high treatment success rate (62.4%).
Conclusions: The most common bacterial pathogens causing LP in children were S. pneumoniae, H. influenzae and M. catarrhalis. Almost detected agents were multi-resistant.
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Article Type: Original Article
ELECTRON J GEN MED, Volume 22, Issue 6, December 2025, Article No: em699
https://doi.org/10.29333/ejgm/17393
Publication date: 09 Nov 2025
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Article Downloads: 9
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