Association between Immune System and Sleep Parameters Among Adults with Bronchial Asthma
Osama H. Al-Jiffri 1, Fadwa M. Al-Sharif 2 *
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1 Department of Medical Laboratory Technology, Faculty of Applied Medical Sciences, King Abdulaziz University, Jeddah, SAUDI ARABIA
* Corresponding Author


Background: Bronchial asthma characterized with inflammation and alteration of immune system activity that induce hyper-reactivity of airways. Inadequate control of associated with impaired sleep quality that adversely influence immunological functions.
Objective: This trial was to measure relation between immune system and sleep parameters among bronchial asthma patients.
Material and Methods: Forty Saudi patients with bronchial asthma consisted of 23 males and 17 females, aged 42-56 year and age matched forty healthy controls consisted of 21 males and 19 females, aged 40-58 year.
Results: The mean value of CD3, CD4, IgG, IgA, IgM, awake time after sleep onset and REM sleep latency were significantly higher in asthma group (A) compared to control group (B). In addition to a significant lower total sleep duration and sleep efficiency in asthma group (A) compared to control group (B). Moreover, CD3, CD4, IgG, IgA, IgM showed a strong inverse relationship with total sleep duration and sleep efficiency and direct relationship with awake time after sleep onset and REM sleep latency in the asthma group (A) (P<0.05).
Conclusion: Immune system response associated with sleep parameters among patients with bronchial asthma.


This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Article Type: Original Article

ELECTRON J GEN MED, 2021 - Volume 18 Issue 2, Article No: em282

Publication date: 07 Mar 2021

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Article Downloads: 527

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