Antidiabetic Treatment In Diabetic Patients With Coronary Artery Disease
Ahmet Soylu 1, Mehmet S. Ülgen 1 * , Mehmet Akif Düzenli
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1 Selcuk University, Meram School of Medicine, Department of Cardiology, Konya, Turkey* Corresponding Author

Abstract

The prevalence of diabetes mellitus (DM) that is about 150 million today is estimated to exceed 300 million by the year 2025 (1). When considered that about half of the patients remain undiagnosed, it can be seen how serious the dimensions of the disease are (2). In the patients with DM more than 90% of whom are consisted by non-insulin dependent diabetes mellitus (NIDDM, Type 2 DM), the disease is a significant risk factor for the development of coronary artery disease (CAD) responsible for 75% of all deaths (3,4). In this group of the patients who generally require antidiabetic treatment inevitably, it is highly important to decide on an appropriate treatment due to the various cardiovascular (CV) effects of the anti-diabetics medications and drugs. In order to help establish this decision, in this review it was tried to investigate antidiabetic drugs after a general approach to CAD pathophysology in diabetic patients, especially in terms of their cardiovascular effects.

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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Article Type: Original Article

EUR J GEN MED, 2007, Volume 4, Issue 4, 190-198

https://doi.org/10.29333/ejgm/82528

Publication date: 15 Oct 2007

Article Views: 1150

Article Downloads: 1010

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