Acute Myocardial Infarction in a Young Woman With Heterozygous Polymorphism for Methylenetetrahydrofolate Reductase and Prothrombin Gene Mutation
Kenan Demir 1 * , Gökhan Altunbaş 1
More Detail
1 Konya Training and Research Hospital, Konya, Turkey* Corresponding Author


Many publications demonstrate a relationship between acute myocardial infarction and genetic mutations. In our case, a 26-yearold young woman was admitted to the hospital with complaints of severe chest pain. She had no risk factors for coronary heart disease but two of her sisters and one of her brothers had suffered sudden cardiac death. DNA samples obtained from peripheral blood were studied by polymerase chain reaction (PCR) and showed mutations in methylenetetrahydrofolate reductase (MTHFR) gene region C677T and heterozygous mutation in prothrombin gene region G20210A.


This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Article Type: Case Report

EUR J GEN MED, 2013, Volume 10, Issue Supplement 1, 66-68

Publication date: 09 Jan 2013

Article Views: 1148

Article Downloads: 613

Open Access References How to cite this article