Thrombocytopenia is the reduction of platelet number to below
normal level. It may be due to the decrease in production, increase
in destruction, abnormal spreading in the body or the laboratory
errors. B12 deficiency is a rarely seen vitamin deficiency in childhood.
It presents with megaloblastic anemia and is difficult to diagnose
because of various clinical findings. Here we would like to present two
cases which were hospitalized to investigate the etiology of anemia
and thrombocytopenia. Cases were detected to have vitamin B12
deficiency which is rarely seen in infantile period. A 12-month old male
and a 16-month old female admitted with complaints of weakness,
bruise and pallor. On physical examination, there was tremor of upper
extremities. Anemia, thrombocytopenia and in peripheral blood
macrocytes were detected as laboratory findings. B12 vitamins were
found to be low. Patients recovered clinically after parenteral vitamin
B12 administration. Laboratory findings also changed into normal.