A case-control study on the temperament and Psychological mood of patients with chronic Hepatitis B
Ebru Fındıklı 1 * , Selma Ateş 1, Bahar Kandemir 1, Mehmet Fatih Karaaslan 1, Mehmet Akif Camkurt 2, Filiz İzci 3, Yasemin Durduran 4, Selçuk Kardaş 1, Mehmet Bitirgen 1
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1 Kahramanmaras Sutcuimam University, Kahramanmaras, Turkey.
2 Afsin Goverment Hospital, Department of Psychiatry, Kahramanmaras, Turkey.
3 Bilim University, Medicine Faculty, Department of Psychiatry, İstanbul, Turkey
4 Necmettin Erbakan University, Konya, Turkey.
* Corresponding Author


To evaluate the personality and temperament traits in patients with chronic hepatitis B in comparison to healthy subjects and to determine whether there is a relation between personality trait and level of anxiety or depression.

Material and Methods:
This was a case-control study in which 67 patients who had been under follow-up with diagnosis of chronic hepatitis B and 103 aged-matched healthy subjects were included. Study participants were asked to complete three self-report questionnaires— Temperament and Character Inventory (TCI) to define personality traits, Beck Depression Inventory (BDI) and Beck Anxiety Inventory (BAI) to evaluate presence and severity of depression and anxiety.

Total and sub-scale scores of five out of seven dimensions of TCI—reward dependence, persistence, self-directedness, cooperativeness, and self-transcence—were significantly higher in Group 1 than Group 2. Total BDI and BAI scores were significantly higher in Group 1 than Group 2 .Significantly more patients had a BDI score of 17 or over in Group 1 than Group 2. There was no significant correlation between total scores of TCI dimensions and total BAI or BDI scores except weak correlations between harm avoidance or self-directedness and total BAI or BDI scores.

In terms of personality trait, patients with chronic hepatitis B exhibit higher reward dependence, persistence, self-directedness, cooperativeness, and self-transcendence from healthy population. The personality traits of patients should be considered during the management of hepatitis B in order to optimize treatment outcome and to prevent development of new mental health problems during the course of the disease.


This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Article Type: Original Article


EUR J GEN MED, 2017 - Volume 14 Issue 3, pp. 58-62

Publication date: 06 Aug 2017

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