The interaction of glutathione and thymoquinone and their antioxidant properties
Ferah Armutcu 1 * , Sumeyya Akyol 2, Omer Akyol 3
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1 Professor of Medical Biochemistry, Private Esencan Hospital Esenyurt, Istanbul, Turkey
2 Associate Professor of Medical Biochemistry, 225 Fluor Daniel Dr., Houston, TX 77479, USA
3 Professor of Medical Biochemistry, 225 Fluor Daniel Dr., Houston, TX 77479, USA
* Corresponding Author

Abstract

Protein S-glutathionylation has been regarded as one of the main mechanisms that control cell signaling and metabolic regulation. Several diseases including cardiovascular diseases, diabetes, neurodegenerative diseases and many types of cancer have been certainly found to be related with S-glutathionylation. It can be regarded as a promising area for therapeutic and diagnostic approaches in many diseases. In this mini review, we aimed to summarize and compare the interaction of glutathione (GSH) and thymoquinone (TQ), and elucidate the possible synergistic mechanisms of antioxidant and other beneficial effects.

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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Article Type: Review Article

https://doi.org/10.29333/ejgm/89493

Electron J Gen Med, 2018 - Volume 15 Issue 4, Article No: em59

Publication date: 15 Apr 2018

Article Views: 321

Article Downloads: 84

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