Factors Affecting Survival in Small Cell Lung Cancer
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Abdullah Sakin 1 * , Erhan Sadık Turgut 2, Muruvvet Aybek 3, Ahmet A. Usta 3, Özgür Koşan 4, Kenan Çelik 5, Savaş Öztürk 5, Murat Koçer 3
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1 Okmeydanı Training and Research Hospital, Medical Oncology Clinic, Istanbul2 Kanuni Sultan Süleyman Training and Research Hospital, Chest Diseases Clinic, Istanbul3 Süleyman Demirel University, Medical Oncology Clinic, Isparta4 Süleyman Demirel University, Department of Biometrics and Genetics, Isparta5 Haseki Training and Research Hospital, Clinic of Internal Medicine, Istanbul* Corresponding Author

Abstract

Background:
Small cell lung cancer (SCLC) constitutes about 15-25 % of lung cancers with high mortality rate. Herein we observed the effect of parameters at the time of diagnosis to survival of cases with SCLC.

Methods:
We evaluated 65 patients who were followed up in our oncology department retrospectively.

Results:
Tumor location and stage at the time of diagnosis, smoking history, accompanying comorbidities, ECOG PS, laboratory parameters and treatments applied in pursuit were evaluated. 3-month survival rate of patients was 75.9%, 50.2% for 6-month, 21.4% for 1 year, and 5.5% for 2 years during follow up. ECOG PS and stage were found statistically significant risk factors in model created to determine overall survival.

Conclusion:
Performance score at the time of diagnosis, stage and presence of liver metastasis are identified as prognostic factors for SCLC and of these factors are quite valuable to predict the clinical outcome.

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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Article Type: Original Article

EUR J GEN MED, 2016, Volume 13, Issue 3, 37-41

https://doi.org/10.29333/ejgm/81903

Publication date: 06 Aug 2016

Article Views: 1305

Article Downloads: 947

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