The lymphoproliferative auto-immune syndrome: a rare cause of peripheral cytopenia
Raida Ben Salah 1  
Mona Snoussi 1,  
Nour Louati 2,  
Chebbi Donia 1,  
Faten Frikha 1,  
Mnif Hela 2,  
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Department of Internal Medicine, Hedi Chaker Hospital Sfax, Tunisia
Center of Transfusion, Hedi Chaker Hospital Sfax, Tunisia
Publish date: 2018-08-23
Electron J Gen Med 2018;15(5):em78
Autoimmune Lymphoproliferative syndrome is an inherited disorder manifesting with autoimmune cytopenia, lymphadenopathy and splenomegaly. The differential diagnosis includes infections, autoimmune disorders or malignancies. The disease is characterized by accumulation of double negative (CD3+ CD4- CD8-) T cells (DNT) in the peripheral blood. Here we report the case of 19 years-old girl that was diagnosed as autoimmune Lymphoproliferative syndrome with a literature review.
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