CASE REPORT
The Chromophobe Renal Cell Carcinoma with Sarcomatoid Differentiation
Sefa Resim 1  
,  
Sevgi Bakaris 2
,  
Rana Citil 2
,  
Erkan Efe 1
,  
 
 
More details
Hide details
1
Department of Urology, Kahramanmaras Sutcu Imam University, Faculty of Medicine, Kahramanmaras, Turkey
2
Department of Pathology, Kahramanmaras Sutcu Imam University, Faculty of Medicine, 46050 Kahramanmaras, Turkey
3
Can Benlioglu, M.D. Department of Urology, 7 Mart Hospital, Kadirli, Turkey
CORRESPONDING AUTHOR
Sefa Resim   

Kahramanmaras Sutcu Imam University Medical Faculty, Department of Urology, 46050, Kahramanmaras-Turkey
Publish date: 2014-01-08
 
Eur J Gen Med 2014;11(Supplement 1):14–17
KEYWORDS
ABSTRACT
We present a rare case of a 52-year-old woman with a chromofobe renal cell carcinoma that had sarcomatoid components. The tumor, 70x60mm in size, was incidentally found by abdominal ultrasonography. An abdominal computed tomography demonstrated a well-demarcated solid tumor arising from the upper pole of the right kidney. Histologically, the tumor was composed of two intermixed distinct morphologic components: a chromophobe renal cell carcinoma and a high-grade spindle cell sarcoma. There was a sarcomatoid area composed of highly atypical spindle cells intermingled with rhabdoid cells. A unique histological finding of this tumor was the presence of calcification and psammoma body formation throughout the tumor. We think that this case supports the existence of a tumor progression pathway from chromofob to sarcomatoid renal cell carcinoma. A literature review on sarcomatoid chromofobe renal cell carcinoma with calcification was performed
eISSN:2516-3507