ORIGINAL ARTICLE
HOW TO MANAGE INTRAUTERINE GROWTH RESTRICTION ASSOCIATED WITH SEVERE PREECLAMPSIA AT 28-34 WEEKS OF GESTATION?
Kazım Gezginç 1  
,  
Ali Acar 1,  
Harun Peru 2,  
Çetin Çelik 1,  
 
 
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1
Selcuk University, Meram Faculty of Medicine, Department of Obstetrics and Gynecology, Konya, Turkey
2
Selcuk University, Meram Faculty of Medicine, Department of Pediatry, Konya, Turkey
Online publish date: 2008-10-15
Publish date: 2008-10-15
 
Electron J Gen Med 2008;5(4):212–215
KEYWORDS:
ABSTRACT:
Aim: To propose optimal management of intrauterine growth restriction (IUGR) cases associated with severe preeclampsia at 28-34 weeks of gestation. Methods: Two hundred pregnant women with severe preeclampsia associated with growth restricted fetuses were followed with doppler velocimetry of umbilical artery between 28-34 weeks of pregnancy. Patients were grouped according to indications for termination of pregnancy, first group consisted of severely affected doppler velocity waveforms (n:100) and the second group consisted of those whose cardiotocography and biophysic profile were unfavorable (n:100). Groups were compared according to perinatal outcomes (cesarean rates, gestational age at delivery, birth weight, Apgar scores and demand for intubation and perinatal deaths). Results: The diagnosis to delivery interval is significantly higher in the second group (p<0.05), whereas there was no significant difference between groups regarding gestational age at delivery and parity (p>0.05). Apgar scores were lower in the first group (p<0.05), and there was increased demand for intubation. Perinatal deaths were also lower in the second group (p<0.05). Cesarean rate was significantly lower compared with first group (p<0.05). Conclusion: Assessment of doppler velocimetry alone may not be enough at decision for termination of pregnancy, biophysic profile and cardiotocography should be added to confirm exact time for delivery of a premature fetus and to improve perinatal outcomes.
CORRESPONDING AUTHOR:
Kazım Gezginç   
Selcuk University, Medical Faculty of Meram, Department of Obstetrics and Gynecology. Akyokuş 42080 Konya/Turkey GSM: 05322707979, Fax: 03322236184
eISSN:2516-3507